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Live-cell imaging to measure BAX recruitment kinetics to mitochondria during apoptosis
The pro-apoptotic BCL2 gene family member, BAX, plays a pivotal role in the intrinsic apoptotic pathway. Under cellular stress, BAX recruitment to the mitochondria occurs when activated BAX forms dimers, then oligomers, to initiate mitochondria outer membrane permeabilization (MOMP), a process criti...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589231/ https://ncbi.nlm.nih.gov/pubmed/28880942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184434 |
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