The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

Delayed or impaired wound healing is a major health issue worldwide, especially in patients with diabetes and atherosclerosis. Here we show that expression of the circular RNA circ-Amotl1 accelerated healing process in a mouse excisional wound model. Further studies showed that ectopic circ-Amotl1 i...

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Pubblicato in:Mol Ther
Autori principali: Yang, Zhen-Guo, Awan, Faryal Mehwish, Du, William W., Zeng, Yan, Lyu, Juanjuan, Wu, De, Gupta, Shaan, Yang, Weining, Yang, Burton B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589065/
https://ncbi.nlm.nih.gov/pubmed/28676341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.022
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