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CD4(+) T cells support establishment of RSV-specific IgG and IgA antibody secreting cells in the upper and lower murine respiratory tract following RSV infection

The RSV vaccine field suffered a major set-back when children were vaccinated with a formalin-inactivated RSV vaccine (FI-RSV). Unexpectedly, the vaccinated children fared worse than unvaccinated children when they were naturally infected with RSV. Mouse models were then developed that implicated th...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Sealy, Robert E., Surman, Sherri L., Hurwitz, Julia L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588898/
https://ncbi.nlm.nih.gov/pubmed/28410812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.03.073
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