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With Unprotected Amino Acids to Tetrazolo Peptidomimetics

Here we describe the direct usage of C,N-unprotected amino acids in the Ugi-tetrazole reactions to produce a novel class of acid-tetrazole compounds. Surprisingly, only tetrazole Ugi product is found and not traces of other possible Ugi type reactions. Based on this reaction pathway we have designed...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chem Commun (Camb)
Hauptverfasser: Madhavachary, Rudrakshula, Wang, Qian, Dömling, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588861/
https://ncbi.nlm.nih.gov/pubmed/28707691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc03370b
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