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Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes
Altered metabolism is a hallmark of cancers, including shifting oxidative phosphorylation to glycolysis and up‐regulating glutaminolysis to divert carbon sources into biosynthetic pathways that promote proliferation and survival. Therefore, metabolic inhibitors represent promising anti‐cancer drugs....
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| Udgivet i: | Immunology |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588769/ https://ncbi.nlm.nih.gov/pubmed/28621843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12777 |
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