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Kinetics and regulation of site-specific endonucleolytic cleavage of human IGF-II mRNAs

Human insulin-like growth factor II (IGF-II) mRNA can be cleaved at a specific site in its 4 kb long 3′-UTR. This yields a stable 3′ cleavage product of 1.8 kb consisting of a 3′-UTR and a poly(A) tail and an unstable 5′ cleavage product containing the IGF-II coding region. After cleavage, the 5′ cl...

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Autores principales: van Dijk, Erwin L., Sussenbach, John S., Holthuizen, P. Elly
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55887/
https://ncbi.nlm.nih.gov/pubmed/11522816
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