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Insulin Prevents Hyperfiltration and Proteinuria but Not Glomerular Hypertrophy and Increases Mesangial Matrix Expansion in Diabetic Rats

OBJECTIVE: The aim of this work was to study the effect of 7 days of strict glycemic control with insulin on glomerular function and structure in streptozotocin (STZ)-diabetic rats. MATERIALS AND METHODS: Three groups of adult male Fischer rats were studied: controls (n = 15), diabetics (n = 15), an...

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Publicat a:Med Princ Pract
Autors principals: Malatiali, Slava, Francis, Issam, Barac-Nieto, Mario
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588318/
https://ncbi.nlm.nih.gov/pubmed/27643698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000450864
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