Association Study of the TREM2 Gene and Identification of a Novel Variant in Exon 2 in Iranian Patients with Late-Onset Alzheimer's Disease

OBJECTIVE: To analyze the association between TREM2 exon 2 variants and late-onset (sporadic) Alzheimer's disease (AD) in an elderly Iranian population. MATERIALS AND METHODS: Exon 2 of TREM2 in a total of 131 AD patients and 157 controls was genotyped using polymerase chain reaction and Sanger...

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Detalhes bibliográficos
Publicado no:Med Princ Pract
Main Authors: Mehrjoo, Zohreh, Najmabadi, Amin, Abedini, Seyedeh Sedigheh, Mohseni, Marzieh, Kamali, Koorosh, Najmabadi, Hossein, Khorram Khorshid, Hamid Reza
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588241/
https://ncbi.nlm.nih.gov/pubmed/26021840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000430842
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