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A cytokine signal inhibitor for rheumatoid arthritis enhances cancer metastasis via depletion of NK cells in an experimental lung metastasis mouse model of colon cancer

Current therapy for rheumatoid arthritis (RA) relies on global suppression of the immune response or specific blockade of inflammatory cytokines. However, it is unclear how immunosuppressants affect patients with cancer. Therefore, in the present study, the effect of three biological agents, tofacit...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Shimaoka, Hideki, Takeno, Shinsuke, Maki, Kenji, Sasaki, Takahide, Hasegawa, Suguru, Yamashita, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588136/
https://ncbi.nlm.nih.gov/pubmed/28928840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6473
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