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Synergistic effects of phenylhexyl isothiocyanate and LY294002 on the PI3K/Akt signaling pathway in HL-60 cells

The aim of the present study was to investigate the synergistic effect of phenylhexyl isothiocyanate (PHI) and LY294002 [an inhibitor of phosphoinositide 3-kinase (PI3K)] on the PI3K/protein kinase B (Akt) signaling pathway, modulating histone acetylation, inhibiting cell viability and inducing apop...

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Publicat a:Oncol Lett
Autors principals: Yang, Huicong, Huang, Yiqun, Zou, Yong, Ma, Xudong
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588084/
https://ncbi.nlm.nih.gov/pubmed/28927052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6556
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