Non-small cell lung cancer PC-9 cells exhibit increased sensitivity to gemcitabine and vinorelbine upon acquiring resistance to EGFR-tyrosine kinase inhibitors

Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (EGFR-TKIs) are widely used for the treatment of non-small cell lung cancers (NSCLCs) harboring EGFR-activating mutations. However, lung cancer cells inevitably acquire resistance to these EGFR-TKIs. The majority of patients whose lu...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Hamamoto, Junko, Yasuda, Hiroyuki, Aizawa, Kaito, Nishino, Makoto, Nukaga, Shigenari, Hirano, Toshiyuki, Kawada, Ichiro, Naoki, Katsuhiko, Betsuyaku, Tomoko, Soejima, Kenzo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588048/
https://ncbi.nlm.nih.gov/pubmed/28927112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6591
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