Inhibition of the ATP Synthase Eliminates the Intrinsic Resistance of Staphylococcus aureus towards Polymyxins

Staphylococcus aureus is intrinsically resistant to polymyxins (polymyxin B and colistin), an important class of cationic antimicrobial peptides used in treatment of Gram-negative bacterial infections. To understand the mechanisms underlying intrinsic polymyxin resistance in S. aureus, we screened t...

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Pubblicato in:mBio
Autori principali: Vestergaard, Martin, Nøhr-Meldgaard, Katrine, Bojer, Martin Saxtorph, Krogsgård Nielsen, Christina, Meyer, Rikke Louise, Slavetinsky, Christoph, Peschel, Andreas, Ingmer, Hanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587909/
https://ncbi.nlm.nih.gov/pubmed/28874470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01114-17
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