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Fibrinogen Activates the Capture of Human Plasminogen by Staphylococcal Fibronectin-Binding Proteins

Invasive bacterial pathogens can capture host plasminogen (Plg) and allow it to form plasmin. This process is of medical importance as surface-bound plasmin promotes bacterial spread by cleaving tissue components and favors immune evasion by degrading opsonins. In Staphylococcus aureus, Plg binding...

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Bibliografske podrobnosti
izdano v:mBio
Main Authors: Herman-Bausier, Philippe, Pietrocola, Giampiero, Foster, Timothy J., Speziale, Pietro, Dufrêne, Yves F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587908/
https://ncbi.nlm.nih.gov/pubmed/28874469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01067-17
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