ALG-5 is a miRNA-associated Argonaute required for proper developmental timing in the Caenorhabditis elegans germline

Caenorhabditis elegans contains 25 Argonautes, of which, ALG-1 and ALG-2 are known to primarily interact with miRNAs. ALG-5 belongs to the AGO subfamily of Argonautes that includes ALG-1 and ALG-2, but its role in small RNA pathways is unknown. We analyzed by high-throughput sequencing the small RNA...

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Udgivet i:Nucleic Acids Res
Main Authors: Brown, Kristen C., Svendsen, Joshua M., Tucci, Rachel M., Montgomery, Brooke E., Montgomery, Taiowa A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587817/
https://ncbi.nlm.nih.gov/pubmed/28645154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx536
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