Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

Mediator is a multi-unit molecular complex that plays a key role in transferring signals from transcriptional regulators to RNA polymerase II in eukaryotes. We have combined biochemical purification of the Saccharomyces cerevisiae Mediator from chromatin with chromatin immunoprecipitation in order t...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Chereji, Răzvan V., Bharatula, Vasudha, Elfving, Nils, Blomberg, Jeanette, Larsson, Miriam, Morozov, Alexandre V., Broach, James R., Björklund, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587782/
https://ncbi.nlm.nih.gov/pubmed/28575439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx491
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