Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium

The fallopian tube epithelium (FTE) has been recognized as a site of origin of high-grade serous ovarian cancer (HGSC). However, the absence of relevant in vitro human models that can recapitulate tissue-specific architecture has hindered our understanding of FTE transformation and initiation of HGS...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yucer, Nur, Holzapfel, Marie, Jenkins Vogel, Tilley, Lenaeus, Lindsay, Ornelas, Loren, Laury, Anna, Sareen, Dhruv, Barrett, Robert, Karlan, Beth Y., Svendsen, Clive N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587694/
https://ncbi.nlm.nih.gov/pubmed/28878359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05519-2
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