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Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model

Septic acute kidney injury (AKI) associates with poor survival rates and often requires renal replacement therapy. Glucocorticoids may pose renal protective effects in sepsis via stimulation of mitochondrial function. Therefore, we studied the mitochondrial effects of dexamethasone in an experimenta...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Schirris, T. J. J., Jansen, J., Mihajlovic, M., van den Heuvel, L. P., Masereeuw, R., Russel, F. G. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587643/
https://ncbi.nlm.nih.gov/pubmed/28878224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10483-y
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