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Effects of Food on the Pharmacokinetics of Omega-3-Carboxylic Acids in Healthy Japanese Male Subjects: A Phase I, Randomized, Open-label, Three-period, Crossover Trial

Aims: Omega-3-carboxylic acids (OM3-CA) contain omega-3 free fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as carboxylic acids. Food intake is known to affect the bioavailability of ethyl ester fatty acid formulations. We conducted a phase I study to investigate th...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Shimada, Hitoshi, Nilsson, Catarina, Noda, Yoshinori, Kim, Hyosung, Lundström, Torbjörn, Yajima, Toshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Atherosclerosis Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587524/
https://ncbi.nlm.nih.gov/pubmed/28344197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.38737
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