Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence

OBJECTIVE: Nicotine’s rewarding effects are mediated through distinct subunits of nAChRs, encoded by different nicotinic cholinergic receptor (CHRN) genes and expressed in discrete regions in the brain. In the present study, we aimed to test the associations between rare variants at CHRN genes and n...

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Veröffentlicht in:Am J Med Genet B Neuropsychiatr Genet
Hauptverfasser: Zuo, Lingjun, Tan, Yunlong, Li, Chiang-Shan R., Wang, Zhiren, Wang, Kesheng, Zhang, Xiangyang, Lin, Xiandong, Chen, Xiangning, Zhong, Chunlong, Wang, Xiaoping, Guo, Xiaoyun, Wang, Jijun, Lu, Lu, Luo, Xingguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587505/
https://ncbi.nlm.nih.gov/pubmed/27473937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32476
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