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Effect of nerve injury on the number of dorsal root ganglion neurons and autotomy behavior in adult Bax-deficient mice

BACKGROUND: The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG) neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal of neurotrophic factors will induce apoptosis in DRG neurons, but this type...

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Detalles Bibliográficos
Publicado en:J Pain Res
Main Authors: Lyu, Chuang, Lyu, Gong-Wei, Martinez, Aurora, Shi, Tie-Jun Sten
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587150/
https://ncbi.nlm.nih.gov/pubmed/28919807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S133087
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