Threshold Effects of Circulating Angiopoietin-Like 3 Levels on Plasma Lipoproteins

CONTEXT: Angiopoietin-like 3 (ANGPTL3) deficiency in plasma due to loss-of-function gene mutations results in familial combined hypobetalipoproteinemia type 2 (FHBL2) in homozygotes. However, the lipid phenotype in heterozygotes is much milder and does not appear to relate directly to ANGPTL3 levels...

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Detaylı Bibliyografya
Yayımlandı:J Clin Endocrinol Metab
Asıl Yazarlar: Fazio, Sergio, Minnier, Jessica, Shapiro, Michael D., Tsimikas, Sotirios, Tarugi, Patrizia, Averna, Maurizio R., Arca, Marcello, Tavori, Hagai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2017
Konular:
Clinical Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587068/
https://ncbi.nlm.nih.gov/pubmed/28633452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-4043
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