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Decomposing the Site Frequency Spectrum: The Impact of Tree Topology on Neutrality Tests

We investigate the dependence of the site frequency spectrum on the topological structure of genealogical trees. We show that basic population genetic statistics, for instance, estimators of θ or neutrality tests such as Tajima’s D, can be decomposed into components of waiting times between coalesce...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Ferretti, Luca, Ledda, Alice, Wiehe, Thomas, Achaz, Guillaume, Ramos-Onsins, Sebastian E.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586374/
https://ncbi.nlm.nih.gov/pubmed/28679545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188763
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