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Decomposing the Site Frequency Spectrum: The Impact of Tree Topology on Neutrality Tests

We investigate the dependence of the site frequency spectrum on the topological structure of genealogical trees. We show that basic population genetic statistics, for instance, estimators of θ or neutrality tests such as Tajima’s D, can be decomposed into components of waiting times between coalesce...

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Vydáno v:Genetics
Hlavní autoři: Ferretti, Luca, Ledda, Alice, Wiehe, Thomas, Achaz, Guillaume, Ramos-Onsins, Sebastian E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586374/
https://ncbi.nlm.nih.gov/pubmed/28679545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188763
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