Membrane‐Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions

BACKGROUND: The MMP (matrix metalloproteinase) family plays diverse and critical roles in directing vascular wall remodeling in atherosclerosis. Unlike secreted‐type MMPs, a member of the membrane‐type MMP family, MT1‐MMP (membrane‐type 1 MMP; MMP14), mediates pericellular extracellular matrix degra...

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Publicado en:J Am Heart Assoc
Autores principales: Barnes, Richard H., Akama, Takeshi, Öhman, Miina K., Woo, Moon‐Sook, Bahr, Julian, Weiss, Stephen J., Eitzman, Daniel T., Chun, Tae‐Hwa
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586255/
https://ncbi.nlm.nih.gov/pubmed/28735290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003693
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