Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina

BACKGROUND: Tetrahydrobiopterin (BH4) is an essential cofactor in multiple metabolic processes and plays an essential role in maintaining the inflammatory and neurovascular homeostasis. In this study, we have investigated the deleterious effects of BH4 deficiency on retinal vasculature during develo...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Rivera, José Carlos, Noueihed, Baraa, Madaan, Ankush, Lahaie, Isabelle, Pan, Jingyi, Belik, Jaques, Chemtob, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586016/
https://ncbi.nlm.nih.gov/pubmed/28874201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0955-x
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