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Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain

AIM: The aim of this study was to develop a novel cabazitaxel bone targeted nanoparticle (NP) system for improved drug delivery to the bone microenvironment. MATERIALS & METHODS: Nanoparticles were developed using poly(D,L-lactic-co-glycolic acid) and cabazitaxel as the core with amino-bisphosph...

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Vydáno v:Nanomedicine (Lond)
Hlavní autoři: Gdowski, Andrew S, Ranjan, Amalendu, Sarker, Marjana R, Vishwanatha, Jamboor K
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585843/
https://ncbi.nlm.nih.gov/pubmed/28805551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2017-0190
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