FEN1 knockdown improves trastuzumab sensitivity in human epidermal growth factor 2-positive breast cancer cells

Trastuzumab has been widely applied as a treatment for human epidermal growth factor 2 (HER2)-overexpressing breast cancer. However, the therapeutic efficacy of trastuzumab is limited. Flap endonuclease 1 (FEN1) is a multifunctional endonuclease that has a crucial role in DNA recombination and repai...

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Vydáno v:Exp Ther Med
Hlavní autoři: Zeng, Xue, Che, Xiaofang, Liu, Yun-Peng, Qu, Xiu-Juan, Xu, Lu, Zhao, Chen-Yang, Zheng, Chun-Lei, Hou, Ke-Zuo, Teng, Yuee
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585749/
https://ncbi.nlm.nih.gov/pubmed/28912877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4873
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