Protein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis

Several protein tyrosine phosphatase non-receptor 22 (PTPN22) single-nucleotide polymorphisms (SNPs) have been significantly related with rheumatoid arthritis (RA) susceptibility. Nevertheless, its potential influence on PTPN22 expression in RA has not been completely elucidated. Furthermore, PTPN22...

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Pubblicato in:Sci Rep
Autori principali: Remuzgo-Martínez, Sara, Genre, Fernanda, Castañeda, Santos, Corrales, Alfonso, Moreno-Fresneda, Pablo, Ubilla, Begoña, Mijares, Verónica, Portilla, Virginia, González-Vela, Jesús, Pina, Trinitario, Ocejo-Vinyals, Gonzalo, Irure-Ventura, Juan, Blanco, Ricardo, Martín, Javier, Llorca, Javier, López-Mejías, Raquel, González-Gay, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585411/
https://ncbi.nlm.nih.gov/pubmed/28874816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10915-9
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