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Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

Cellular processes often depend on interactions between proteins and the formation of macromolecular complexes. The impairment of such interactions can lead to deregulation of pathways resulting in disease states, and it is hence crucial to gain insights into the nature of macromolecular assemblies....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bertoni, Martino, Kiefer, Florian, Biasini, Marco, Bordoli, Lorenza, Schwede, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585393/
https://ncbi.nlm.nih.gov/pubmed/28874689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09654-8
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