Natural (∆(9)-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB(1) receptor

Natural cannabinoids and their synthetic substitutes are the most widely used recreational drugs. Numerous clinical cases describe acute toxic symptoms and neurological consequences following inhalation of the mixture of synthetic cannabinoids known as “Spice.” Here we report that an intraperitoneal...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Malyshevskaya, Olga, Aritake, Kosuke, Kaushik, Mahesh K., Uchiyama, Nahoko, Cherasse, Yoan, Kikura-Hanajiri, Ruri, Urade, Yoshihiro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585372/
https://ncbi.nlm.nih.gov/pubmed/28874764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10447-2
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