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Decidualisation and placentation defects are a major cause of age-related reproductive decline

Mammalian reproductive performance declines rapidly with advanced maternal age. This effect is largely attributed to the exponential increase in chromosome segregation errors in the oocyte with age. Yet many pregnancy complications and birth defects that become more frequent in older mothers, in bot...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Woods, Laura, Perez-Garcia, Vicente, Kieckbusch, Jens, Wang, Xiaoqiu, DeMayo, Francesco, Colucci, Francesco, Hemberger, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585348/
https://ncbi.nlm.nih.gov/pubmed/28874785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00308-x
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