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Topologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation
Developmental genes in metazoan genomes are surrounded by dense clusters of conserved noncoding elements (CNEs). CNEs exhibit unexplained extreme levels of sequence conservation, with many acting as developmental long-range enhancers. Clusters of CNEs define the span of regulatory inputs for many im...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585340/ https://ncbi.nlm.nih.gov/pubmed/28874668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00524-5 |
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