Contribution of C1485T mutation in the HBx gene to human and murine hepatocarcinogenesis

Although Hepatitis B virus (HBV) X gene mutations are frequently detected in HBV-related human hepatocellular carcinoma (HCC) patients, causative HBx mutations in the development of HCC have not yet been determined. We herein identified C1485T and C1653T mutations in the HBx gene as independent risk...

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Udgivet i:Sci Rep
Main Authors: Hagiwara, Satoru, Nishida, Naoshi, Park, Ah-Mee, Komeda, Yoriaki, Sakurai, Toshiharu, Watanabe, Tomohiro, Kudo, Masatoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585302/
https://ncbi.nlm.nih.gov/pubmed/28874700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10570-0
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