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The role of histone modification and a regulatory single-nucleotide polymorphism (rs2071166) in the Cx43 promoter in patients with TOF

Abnormal level of Cx43 expression could result in CHD. Epigenetic modification and disease-associated, non-coding SNPs might influence gene transcription and expression. Our study aimed to determine the role of histone modification and an rSNP (rs2071166) in the Cx43 promoter in patients with TOF. O...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gu, Ruoyi, Xu, Jun, Lin, Yixiang, Sheng, Wei, Ma, Duan, Ma, Xiaojing, Huang, Guoying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585261/
https://ncbi.nlm.nih.gov/pubmed/28874875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10756-6
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