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Selection for energy efficiency drives strand-biased gene distribution in prokaryotes
Lagging-strand genes accumulate more deleterious mutations. Genes are thus preferably located on the leading strand, an observation known as strand-biased gene distribution (SGD). Despite of this mechanistic understanding, a satisfactory quantitative model is still lacking. Replication-transcription...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585166/ https://ncbi.nlm.nih.gov/pubmed/28874819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11159-3 |
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