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Screening for Natural Inhibitors of Topoisomerases I from Rhamnus davurica by Affinity Ultrafiltration and High-Performance Liquid Chromatography–Mass Spectrometry
Topoisomerase I (Topo I) catalyzes topological interconversion of duplex DNA during DNA replication and transcription, and has been deemed as important antineoplastic targets. In this study, the fraction R.d-60 from ethyl acetate extracts of Rhamnus davurica showed higher inhibitory rates against SG...
Enregistré dans:
Publié dans: | Front Plant Sci |
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Auteurs principaux: | , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Frontiers Media S.A.
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585147/ https://ncbi.nlm.nih.gov/pubmed/28919906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2017.01521 |
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