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Screening for Natural Inhibitors of Topoisomerases I from Rhamnus davurica by Affinity Ultrafiltration and High-Performance Liquid Chromatography–Mass Spectrometry

Topoisomerase I (Topo I) catalyzes topological interconversion of duplex DNA during DNA replication and transcription, and has been deemed as important antineoplastic targets. In this study, the fraction R.d-60 from ethyl acetate extracts of Rhamnus davurica showed higher inhibitory rates against SG...

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Bibliografske podrobnosti
izdano v:Front Plant Sci
Main Authors: Chen, Guilin, Guo, Mingquan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585147/
https://ncbi.nlm.nih.gov/pubmed/28919906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2017.01521
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