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Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs

In addition to the cap-dependent mechanism, eukaryotic initiation of translation can occur by a cap-independent mechanism which directs ribosomes to defined start codons enabled by internal ribosome entry site (IRES) elements. IRES elements from poliovirus and encephalomyocarditis virus are often us...

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Detalhes bibliográficos
Main Authors: Hennecke, Meike, Kwissa, Marcin, Metzger, Karin, Oumard, André, Kröger, Andrea, Schirmbeck, Reinhold, Reimann, Jörg, Hauser, Hansjörg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55851/
https://ncbi.nlm.nih.gov/pubmed/11504870
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