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Valproate Increases Dopamine Transporter Expression through Histone Acetylation and Enhanced Promoter Binding of Nurr1

The dopamine transporter (DAT) is the key regulator of dopaminergic transmission and is a target of several xenobiotics, including pesticides and pharmacological agents. Previously, we identified a prominent role for histone deacetylases in the regulation of DAT expression. Here, we utilized a rat d...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Green, Ashley L., Zhan, Le, Eid, Aseel, Zarbl, Helmut, Guo, Grace L., Richardson, Jason R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585058/
https://ncbi.nlm.nih.gov/pubmed/28743636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.07.020
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