Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation

Pore-forming toxins are potent virulence factors secreted by a large array of bacteria. Here, we deciphered the action of ExlA from Pseudomonas aeruginosa and ShlA from Serratia marcescens on host cell-cell junctions. ExlA and ShlA are two members of a unique family of pore-forming toxins secreted b...

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Vydáno v:PLoS Pathog
Hlavní autoři: Reboud, Emeline, Bouillot, Stéphanie, Patot, Sabine, Béganton, Benoît, Attrée, Ina, Huber, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584975/
https://ncbi.nlm.nih.gov/pubmed/28832671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006579
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