Differential localization of HDAC4 orchestrates muscle differentiation

The class II histone deacetylases HDAC4 and HDAC5 interact specifically with the myogenic MEF2 transcription factor and repress its activity. Here we show that HDAC4 is cytoplasmic during myoblast differentiation, but relocates to the nucleus once fusion has occurred. Inappropriate nuclear entry of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Miska, Eric A., Langley, Emma, Wolf, Daniel, Karlsson, Christina, Pines, Jon, Kouzarides, Tony
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2001
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC55849/
https://ncbi.nlm.nih.gov/pubmed/11504882
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller