Longistyline C acts antidepressant in vivo and neuroprotection in vitro against glutamate-induced cytotoxicity by regulating NMDAR/NR2B-ERK pathway in PC12 cells

Depressive disorder is a common psychiatric disease which ranks among the leading cause of disability worldwide. The antidepressants presently used had low cure rate and caused a variety of side-effects. The screening of antidepressant drugs is usually used classic behavioural tests and neuroprotect...

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Foilsithe in:PLoS One
Main Authors: Liu, Yamin, Zhao, Ning, Li, Chenchen, Chang, Qi, Liu, Xinmin, Liao, Yonghong, Pan, Ruile
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584824/
https://ncbi.nlm.nih.gov/pubmed/28873095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183702
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