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What makes oncogenes mutually exclusive?
Cancer is driven by mutations in genes whose products participate in major signaling pathways that fuel cell proliferation and survival. It is easy to assume that the more of these so-called driver mutations a tumor accumulates, the faster it progresses. However, this does not appear to be the case:...
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| Published in: | Small GTPases |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584735/ https://ncbi.nlm.nih.gov/pubmed/27416373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1212689 |
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