Blood brain barrier-adapted precision medicine therapy for pediatric brain tumors

Targeted chemotherapeutics provide a promising new treatment option in neuro-oncology. The ability of these compounds to penetrate the blood brain barrier is crucial for their successful incorporation into patient care. “CNS Targeted Agent Prediction” (CNS-TAP) is a multi-institutional and multi-dis...

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Published in:Transl Res
Main Authors: Marini, Bernard L., Benitez, Lydia L., Zureick, Andrew H., Salloum, Ralph, Gauthier, Angela C., Brown, Julia, Wu, Yi-Mi, Robinson, Dan R., Kumar, Chandan, Lonigro, Robert, Vats, Pankaj, Cao, Xuhong, Kasaian, Katayoon, Anderson, Bailey, Mullan, Brendan, Chandler, Benjamin, Linzey, Joseph R., Camelo-Piragua, Sandra I., Venneti, Sriram, Mc Keever, Paul E., McFadden, Kathryn A., Lieberman, Andrew P., Brown, Noah, Shao, Lina, Leonard, Marcia A. S., Junck, Larry, McKean, Erin, Maher, Cormac O., Garton, Hugh J. L., Muraszko, Karin M., Hervey-Jumper, Shawn, Mulcahy-Levy, Jean M., Green, Adam, Hoffman, Lindsey M., Dorris, Katie, Vitanza, Nicholas A., Wang, Joanne, Schwartz, Jonathan, Lulla, Rishi, Smiley, Natasha Pillay, Bornhorst, Miriam, Haas-Kogan, Daphne A., Robertson, Patricia L., Chinnaiyan, Arul M., Mody, Rajen, Koschmann, Carl
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584679/
https://ncbi.nlm.nih.gov/pubmed/28860053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.08.001
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