Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress

Membrane-associated RING-CH protein 2 (MARCH2), a member of the MARCH family, functions in vesicle trafficking and autophagy regulation. In this study, we established MARCH2 knockout HCT116 cell lines using CRISPR/Cas9-mediated genome editing to evaluate the role of MARCH2 in colon cancer in vitro a...

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Vydáno v:Cell Death Dis
Hlavní autoři: Xia, Dan, Ji, Wanli, Xu, Chentong, Lin, Xin, Wang, Xiaokun, Xia, Yan, Lv, Ping, Song, Quansheng, Ma, Dalong, Chen, Yingyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584615/
https://ncbi.nlm.nih.gov/pubmed/28749466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.347
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