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ETV6 in Hematopoiesis and Leukemia Predisposition
The ETV6 (also known as TEL) gene encodes a transcriptional repressor that plays a critical role in hematopoiesis and in embryonic development. While somatic ETV6 translocations and missense mutations are frequently observed in human cancers, the role of ETV6 in malignant transformation was unclear....
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Published in: | Semin Hematol |
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Main Authors: | , |
Format: | Artigo |
Language: | Inglês |
Published: |
2017
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584538/ https://ncbi.nlm.nih.gov/pubmed/28637624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2017.04.005 |
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