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ETV6 in Hematopoiesis and Leukemia Predisposition

The ETV6 (also known as TEL) gene encodes a transcriptional repressor that plays a critical role in hematopoiesis and in embryonic development. While somatic ETV6 translocations and missense mutations are frequently observed in human cancers, the role of ETV6 in malignant transformation was unclear....

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Bibliographic Details
Published in:Semin Hematol
Main Authors: Hock, Hanno, Shimamura, Akiko
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584538/
https://ncbi.nlm.nih.gov/pubmed/28637624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2017.04.005
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