Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia

Protective interactions with bystander cells in micro-environmental niches, such as lymph nodes (LNs), contribute to survival and therapy resistance of chronic lymphocytic leukemia (CLL) cells. This is caused by a shift in expression of B-cell lymphoma 2 (BCL-2) family members. Pro-survival proteins...

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Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: van Attekum, M H A, Terpstra, S, Slinger, E, von Lindern, M, Moerland, P D, Jongejan, A, Kater, A P, Eldering, E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584520/
https://ncbi.nlm.nih.gov/pubmed/28192408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.515
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