Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation

PURPOSE: Limbal epithelial stem cells (LSCs), located in the basal layer of the corneal epithelium in the corneal limbus, are vital for maintaining the corneal epithelium. LSCs have a high capacity of self-renewal with increased potential for error-free proliferation and poor differentiation. To dat...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Gesteira, Tarsis F., Sun, Mingxia, Coulson-Thomas, Yvette M., Yamaguchi, Yu, Yeh, Lung-Kun, Hascall, Vincent, Coulson-Thomas, Vivien J.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2017
Fag:
Cornea
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584473/
https://ncbi.nlm.nih.gov/pubmed/28863216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22326
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