Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer

BET bromodomain inhibitors, which have an antitumoral effect against various solid cancer tumor types, have not been studied in detail in luminal breast cancer, despite the prevalence of this subtype of mammary malignancy. Here we demonstrate that the BET bromodomain inhibitor JQ1 exerts growth-inhi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pérez-Salvia, Montserrat, Simó-Riudalbas, Laia, Llinàs-Arias, Pere, Roa, Laura, Setien, Fernando, Soler, Marta, de Moura, Manuel Castro, Bradner, James E., Gonzalez-Suarez, Eva, Moutinho, Catia, Esteller, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584274/
https://ncbi.nlm.nih.gov/pubmed/28881673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18255
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