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Preliminary biological evaluation of (18)F-AlF-NOTA-MAL-Cys-Annexin V as a novel apoptosis imaging agent

A novel annexin V derivative (Cys-Annexin V) with a single cysteine residue at its C-terminal has been successfully labeled site-specifically with NOTA-maleimide aluminum [(18)F]fluoride complexation and evaluated it as a novel apoptosis agent in vitro and in vivo. The total synthesis time of (18)F-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lu, Chunxiong, Jiang, Quanfu, Hu, Minjin, Tan, Cheng, Yu, Huixin, Hua, Zichun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584233/
https://ncbi.nlm.nih.gov/pubmed/28881632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16994
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