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Low PCA3 expression is a marker of poor differentiation in localized prostate tumors: exploratory analysis from 12,076 patients

BACKGROUND: Prostate cancer antigen 3 (PCA3) is a prostate cancer diagnostic biomarker that has been clinically validated. The limitations of the diagnostic role of PCA3 in initial biopsy and the prognostic role are not well established. Here, we elucidate the limitations of tissue PCA3 to predict h...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Alshalalfa, Mohammed, Verhaegh, Gerald W., Gibb, Ewan A., Santiago-Jiménez, Maria, Erho, Nicholas, Jordan, Jennifer, Yousefi, Kasra, Lam, Lucia L.C., Kolisnik, Tyler, Chelissery, Jijumon, Seiler, Roland, Ross, Ashley E., Karnes, R. Jeffrey, Schaeffer, Edward M., Lotan, Tamara T., Den, Robert B., Freedland, Stephen J., Davicioni, Elai, Klein, Eric A., Schalken, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584206/
https://ncbi.nlm.nih.gov/pubmed/28881605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15133
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